After months of speculation, Democratic State Sen. Leticia Van de Putte says she’s running for San Antonio mayor.

The announcement comes just a couple weeks after Van de Putte suffered a huge loss to Republican Dan Patrick in the Lt. Governor’s race. But although she lost big to Patrick two weeks ago, Van de Putte won more than 50 percent of the Bexar County vote. The city election is May 9th.

Meantime, Van de Putte’s decision to run sets up a political “domino effect” among state lawmakers from San Antonio. State Rep. Mike Villarreal (D, District 123) is also running for mayor — and has resigned from the House.

And two other Texas House members from San Antonio have expressed interested in running for Van de Putte’s Senate seat. Today, State Rep. Trey Martinez Fischer (D, District 116) officially declared he is a candidate. And State Rep. Jose Menendez (D, District 124) has already publicly indicated he would be interested.

Van de Putte plans let Gov. Rick Perry know today her intention to resign from the Senate, so he can call for a special election.